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UPF (Universitat Pompeu Fabra)

UPF (Universitat Pompeu Fabra)

La UPF es una universidad joven, pública y moderna, creada en 1990 con voluntad de convertirse en una universidad de referencia en Europa. Distinguida por el Ministerio de Educación como Campus de Excelencia Internacional (CEI), los indicadores en docencia, investigación e internacionalización de la UPF avalan su posición como centro de referencia dentro del sistema español y europeo. Asimismo, en los últimos años la Universidad ha comenzado a aparecer con fuerza en rankings de prestigio internacional. Dirección: Plaça de la Mercè, 10, 08002 Barcelona. Teléfono: 935 42 20 00. www.upf.edu/es

Estudiar el cerebro bajo los efectos del LSD aporta valiosos datos a la psicología

Fuente: UPF | Publicado: 01-02-2018
Según se desprende de un trabajo publicado en diciembre en la revista Scientific Reports, del que son autores Gustavo Deco, director del Centro de Cognición y Cerebro, conjuntamente con Selen Atasoy, investigadora doctoral de su equipo.
Derechos: Las primeras imágenes modernas del cerebro bajo los efectos del LSD. UPF.
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La dietilamida del ácido lisérgico, más conocida como LSD, es una de las sustancias psicotrópicas más potentes que se conoce, e induce a estados alterados de conciencia, a veces comparados a los estados propios de la esquizofrenia o la experiencia mística. El estudio de los efectos sobre el cerebro de los compuestos psicodélicos como el LSD son muy relevantes para el estudio de rasgos psicológicos como la personalidad, la creatividad y también para la mejor caracterización de enfermedades neurológicas y psiquiátricas.


Un artículo publicado en diciembre en Scientific Reports aplica una metodología analítica nueva y potente para estudiar la dinámica de los estados cerebrales en estados psicodélicos inducidos con LSD. Entre los autores del trabajo está Gustavo Deco, director del Centro de Cognición y Cerebro (CBC) y profesor de investigación ICREA del Departamento de Tecnologías de la Información y las Comunicaciones (DTIC) de la UPF, conjuntamente con Selen Atasoy, investigadora doctoral de su equipo y primera autora del trabajo. Además, han participado investigadores vinculados al Imperial College de Londres y a la Universidad  de Oxford (Reino Unido) y a la Universidad de Aarhus (Dinamarca).



En la parte experimental participaron doce individuos que fueron asignados a seis posibles condiciones en estudio: LSD; placebo; LSD o placebo, mientras escuchaban música; LSD o placebo, después de la sesión musical. Explorar los efectos combinados de la música y los estados psicodélicos inducidos por LSD brindó la oportunidad de revelar no sólo los cambios dinámicos inducidos por LSD en el cerebro, sino también como estas dinámicas se ven afectadas por la presencia de estímulos complejos y naturales como la música.


El nuevo método puesto a punto por los investigadores ha permitido descomponer los datos provenientes de resonancia magnética funcional (IRMf, en inglés fMRI) de cerebros en estado de reposo y bajo los efectos del LSD, para un conjunto de estados independientes. Los estados de la inteligencia se definen como patrones espaciales formados por una actividad completamente sincronizada, cada una asociada a una longitud de onda espacial diferente; que los autores llaman: connectoma armónico.


"La descomposición única de la actividad cortical en una suma de estados específicos de frecuencia nos permite caracterizar no sólo el contenido de frecuencia dominante según sea la actividad cerebral bajo LSD y / o placebo, sino también la dinámica subyacente en términos de distribución de frecuencias entre un repertorio posible de estos estados ", comenta Gustavo Deco.



Para caracterizar la actividad cerebral durante el estado psicodélico inducido por LSD, los autores han centrado su evaluación en dos propiedades fundamentales de los estados cerebrales: el poder o fuerza de activación por unidad de tiempo según IRMf, y la energía o contribución ponderada de esta activación a la dinámica cortical. Dos parámetros que se han encontrado alterados bajo los efectos del LSD. Además, se ha visto que LSD provoca una reorganización de la dinámica cerebral cercana al estado crítico, es decir, un estado que se sitúa en el límite entre dos tendencias opuestas de connexión neuronal: un orden intermitente y un desorden caótico.


Los hallazgos actuales destacan el valor de concebir la función cerebral global y los estados subjetivos relacionados en términos de activación dinámica de los estados del cerebro armónico. Es importante destacar que esta descomposición armónica del connectoma específico de la actividad cortical permite la evaluación de las propiedades fundamentales de los estados del cerebro, y aporta a las neurociencias nuevas e innovadoras herramientas basadas en conceptos físicos bien estudiados.


<iframe width="555" height="683" src="https://www.youtube.com/embed/kvalFfavNpU" frameborder="0" allow="autoplay; encrypted-media" allowfullscreen></iframe>


Artículo de referencia: Selen Atasoy, Leor Roseman, Mendel Kaelen, Morten L. Kringelbach, Gustavo Deco, Robin L. Carhart-Harris (2017), “Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD”, Scientific Reports 7, Article number: 17661, doi:10.1038/s41598-017-17546-0.

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businesses for sale 02-03-2018 12:03
 
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Hasta el punto de que el producto se vende incluso a plazos,resultados de futbol pues la firma deportiva permite fraccionar el pago en tres cuotas. En el podium le acompañan la camiseta de Francia y la de España,camisetas de futbol baratas siempre entre las más compradas. Muy destacable también el elevado puesto en el camisetas de futbol 2018 ranking de equipaciones menos conocidas como la de Islandia,david de gea camiseta México o Corea del Sur.La Copa del Mundo de Rusia 2018 está a la vuelta de la esquina,thiago camiseta los jugadores saltarán a la cancha con las armaduras para la batalla y estas suelen ser un gran atractivo para la tribuna, pues es con estas camisetas que se elaboran recuerdos memorables,Blogger.Com para bien y para mal, hoy en día los colores de cada una son los clásicos,Squarespace.Com pero la modernidad se ha llenado de ellas.En un operativo,mundiales de futbol las autoridades confiscaron más de cinco mil camisetas falsas de la Selección Colombia de fútbol y futbol primera otras 35 toneladas de mercancía contrabando en Bogotá y Cali,Jordi Alba informó hoy la Fiscalía. El hallanamiento dejó nueve capturados.
23-06-2018 08:06

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